General Cell Based Assays
General Cell Based Assays
Thermo Scientific™ GeneBLAzer™ EDNRA-NFAT-bla HEK 293T Cells
GeneBLAzer™ EDNRA-NFAT-bla HEK293T cells contain the human Endothelin Type A Recpetor (EDNRA) stably integrated into the CellSensor™ NFAT-bla HEK293T cell line.
Thermo Scientific™ BacMam Akt [pThr308] Cellular Assay Kit
The combination of baculovirus-mediated gene delivery (BacMam) with LanthaScreen™ Cellular Assay technology enables a platform for the analysis of specific posttranslational modifications of various substrates including AKT.
Thermo Scientific™ GeneBLAzer™ M3-NFAT-bla CHO-K1 Cells
GeneBLAzer™ M3-NFAT-bla CHO-K1 cells contain the human Acetylcholine (Muscarinic) Receptor 3 (M3) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ BacMam Akt [pSer473] Cellular Assay Kit
The combination of baculovirus-mediated gene delivery (BacMam) with LanthaScreen™ Cellular Assay technology enables a platform for the analysis of specific posttranslational modifications of various substrates including AKT.
Thermo Scientific™ LanthaScreen™ IGF-1R GripTite™ Cell Line
The IGF-1R/PI3K/AKT pathway mediates signals for cell growth, cell survival, transcription, translation, and glucose uptake. IGF-1R is a receptor tyrosine kinase (RTK) that resides at the top of the pathway.
Thermo Scientific™ GeneBLAzer™ RAR alpha DA Assay Kit
The GeneBLAzer™RAR alpha DA (Division Arrested) and RAR alpha-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human retinoic acid receptor alpha fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK293T cell line.
Thermo Scientific™ GeneBLAzer™ ADRB2-CRE-bla CHO-K1 Cells
The GeneBLAzer™ ADRB2-CRE-bla CHO-K1 cells contain the human Adrenergic Beta-2 Receptor (ADRB2), (Accession No. NM_000024.3) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ Bradykinin-B2-NFAT-bla CHO-K1 Cells
GeneBLAzer™ Bradykinin-B2-NFAT-bla CHO-K1 cells contain the human Bradykinin Receptor B2 (B2) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ M1-bla U2OS Cells
Tango™ M1-bla U2OS cells contain the human muscarinic M1 receptor (CHRM1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ CellSensor™ CRE HEK 293T DA Assay Kit
The CellSensor™ CRE HEK 293T DA (Division Arrested) cells contains a beta-lactamase (bla) reporter gene under control of a cAMP response element (CRE) stably integrated into HEK293T cells.
Thermo Scientific™ LanthaScreen™ ATF2 (19-106) A549 Cell Line
Contains a fusion protein consisting of GFP and a fragment encoding for aa 19-106 of ATF2 under the control of a CMV promotor
Thermo Scientific™ LanthaScreen™ STAT5 (JAK2 V617F) U2OS Cell Line
LanthaScreen™ GFP Cellular Assays allow for the analysis of post-translational modifications for a number of target proteins in an live-cell context.
Thermo Scientific™ Tango™ CCR1-bla U2OS Cells
The Tango™ CCR1 -bla U2OS cells contain the human Chemokine (C-C Motif) Receptor 1 (CCR1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ CellSensor™ GAS-bla ME-180 Cell Line
The CellSensor™ GAS-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Gamma Activated Sequence (GAS) response element stably integrated into ME-180 cells.
Thermo Scientific™ GeneBLAzer™ LXRβ-UAS-bla HEK 293T Cells
LXR beta-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human Liver-X receptor-beta (LXR beta) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.