Test
In the LanthaScreen™ Eu Kinase Binding Assay, binding of an Alexa Fluor™ conjugate or tracer such as Kinase Tracer 236 to a kinase is detected by addition of a Eu-labeled anti-tag antibody.
The CRE-bla Jurkat cell line contains a beta-lactamase reporter gene under control of a cAMP response element (CRE) stably integrated into Jurkat cells.
LanthaScreen™ GFP Cellular Assays allow for the analysis of post-translational modifications for a number of target proteins in an live-cell context.
Neurotrophins (NGF, BDNF, NT-3, and NT-4) and their transmembrane receptors (TrkA, TrkB, TrkC, and P75NTR) play important roles in the regulation of neuronal and non-neuronal cell proliferation, differentiation, survival, and death.
GeneBLAzer™ GPR24-Gqi5-NFAT-bla CHO-K1 cells contain the human Melanin-concetrating hormone receptor (GPR24) stably integrated into the GeneBLAzer™ Gqi5-NFAT-bla CHO-K1 cell line.
The GeneBLAzer ™ ADRB1-CRE-bla CHO-K1 cells contain the human Adrenergic Beta-1 Receptor (ADRB1), (Accession No. NM_000684) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
T-REx™ Tango™ P2RY14-bla U2OS cells contain the human purinergic receptor P2Y14 (P2RY14) under doxycycline inducible control linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
GeneBLAzer MCHR2-NFAT-bla CHO-K1 cells contain the human melanin-concentrating hormone receptor 2 (GPR145) stably integrated into the CellSensor NFAT-bla CHO-K1 parental cell line.
GeneBLAzer™ FPRL-1-Gα15-NFAT-bla CHO-K1 cells contain the human Formyl Peptide Like Receptor 1 (FPRL-1) stably integrated into the GeneBLAzer™ Gα15-NFAT-bla CHO-K1 cell line.
GeneBLAzer™PR DA (Division Arrested) cells and PR-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human Progesterone Receptor (PR) fused to the DNAbinding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
GeneBLAzer™ GCGR-CRE-bla CHO-K1 Cells contain the human glucagon receptor (GCGR).
The GeneBLAzer™ ADRB2-CRE-bla CHO-K1 cells contain the human Adrenergic Beta-2 Receptor (ADRB2), (Accession No. NM_000024.3) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
The Tango™ ADORA1-bla U2OS cells contain the human Adenosine A1 receptor (ADORA1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
The GeneBLAzer™ C5AR1-Gα15 CHO-K1 DA (Division Arrested) cells contain the human Complement Component 5a Receptor 1 (C5AR1) stably integrated into the GeneBLAzer™ Gα15-NFAT-bla CHO-K1 cell line.
The CellSensor™ CRE-bla HEK 293T cell line contains the b-lactamase reporter gene under control of the cAMP response element (CRE).