General Cell Based Assays
General Cell Based Assays
Thermo Scientific™ LanthaScreen™ STAT1 U2OS Cell Line
The JAK/STAT1 signaling pathway is known to be activated by type I/II interferons such as interferon-gamma and interferon-alpha.
Thermo Scientific™ GeneBLAzer™ EDG3-Gα15 HEK 293T DA Assay Kit
GeneBLAzer™ EDG3-Gα15 HEK 293T DA (Division Arrested) cells and EDG3-Gα15-NFAT-bla HEK 293T cells contain the human EDG3 receptor stably integrated in the GeneBLAzer™ Gα15-NFAT-bla HEK 293T cell line.
Thermo Scientific™ UAS-bla HEK 293T Master Cell Line
The UAS-bla HEK 293T Master Cell Line consists of HEK 293T cells stably transfected with a UAS-bla fusion construct.
Thermo Scientific™ GeneBLAzer™ NPSR1-B-NFAT-bla CHO-K1 Cells
The GeneBLAzer™ NPSR1-B-NFAT-bla CHO-K1 cells contain the human Neuropeptide S Receptor 1-Isoform B (NPSR1-B), (Accession # NP_997056) stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ GRPR-NFAT-bla CHO-K1 Cells
The GeneBLAzer™ GRPR-NFAT-bla CHO-K1 cells contain the human Gastrin Releasing Peptide Receptor (GRPR) stably integrated into the GeneBLAzer™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ GeneBLAzer™ P2RY4-NFAT-bla CHO-K1 Cells
GeneBLAzer™ P2RY4-NFAT-bla CHO-K1 cells contain the human Purinergic Receptor P2Y4 (P2RY4), stably integrated into the CellSensor™ NFAT-bla CHO-K1 cell line.
Thermo Scientific™ Tango™ EDNRA-bla U2OS Cells
The Tango™ EDNRA-bla U2OS cells contain the human Endothelin Receptor A (EDNRA) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ RXR beta DA Assay Kit
GeneBLAzer™RXR beta DA (Division Arrested) cells and RXR beta-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human Retinoid X Receptor beta (RXR beta) fused to the DNA-binding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
Thermo Scientific™ Tango™ SSTR5-bla U2OS DA Assay Kit
The Tango™ SSTR5-bla U2OS cells contain the human Somatostatin Receptor 5 (SSTR5) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ GeneBLAzer™ EDNRA-NFAT-bla HEK 293T Cells
GeneBLAzer™ EDNRA-NFAT-bla HEK293T cells contain the human Endothelin Type A Recpetor (EDNRA) stably integrated into the CellSensor™ NFAT-bla HEK293T cell line.
Thermo Scientific™ Tango™ TACR3-bla U2OS Cells
The Tango™ TACR3-bla U2OS cells contain the human Tachykinin Receptor 3 (TACR3) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ Tango™ GPR21-bla U2OS Cells
Tango™ GPR21-bla U2OS cells contain the orphan human G-protein Coupled Receptor 21 (GPR21) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ LanthaScreen™ STAT3 GripTite™ Cell Line
The JAK/STAT3 signaling pathway is known to be activated by cytokines such as IL-6. In this pathway, binding of IL-6 to its cell-surface receptors results in the activation of JAKs, which in turn phosphoactivate STAT3 proteins at a specific tyrosine residue (Y705).
Thermo Scientific™ Tango™ GALR1-bla U2OS Cells
The Tango™ GALR1 -bla U2OS cells contain the human Galanin Receptor 1 (GALR1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Thermo Scientific™ Tango™ EDG6-bla U2OS DA Assay Kit
The Tango™ EDG6-bla U2OS cells contain the human Endothelial Differentiation, Lysophosphatidic Acid G-protein-coupled Receptor, 6 (EDG6) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.