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Tocris Bioscience™ BIRB 796
High affinity and selective p38 kinase inhibitor
Brand: Tocris Bioscience™ 5989/10
126.99 EUR valid until 2024-12-16
Use promo code "21630" to get your promotional price.
This item is not returnable.
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Description
BIRB 796 is a high affinity and selective p38 kinase inhibitor (Kd = 50-100 pM). Exhibits no significant inhibition on a panel of related kinases. Inhibits LPS-induced TNFα production in human PBMCs and whole blood (IC50 values are 21 and 960 nM, respectively). Also inhibits JNK2α2 and c-Raf-1 (IC50 values are 98 nM and 1.4 μM, respectively). Cell permeable.Specifications
| N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N′-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea | |
| Doramapimod | |
| p38 Inhibitors | |
| 527.66 |
| 285983-48-4 | |
| 10 mg | |
| C31H37N5O3 | |
| 0.98 |