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Tocris Bioscience™ FTY 720

Potent S1P receptor agonist; also immunosuppressant

Brand: Tocris Bioscience™ 6176/50

416.40 EUR valid until 2024-12-16
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Product Code. 18761508

544.00 € / 50mg

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Description

FTY 720 is an S1P receptor agonist; undergoes phosphorylation by sphingosine kinase 2, which then binds S1P1,3,4 and 5 receptors (EC50 values are 0.3 - 0.6 nM for S1P1, 4 and 5 and ∼3 nM for S1P3). Immunosuppressant; sequesters lymphocytes in lymph nodes, reducing autoimmune response. Suppresses the development of EAE (an in vivo model of MS). Orally bioavailable and blood-brain barrier permeable.

Specifications

Product Type	Agonist
CAS	162359-56-0
Formula Weight	343.93g/mol
Content And Storage	Store at -20°C
Quantity	50 mg

Target Proteins	Sphingosine-1-phosphate Receptor
Molecular Formula	C₁₉H₃₃NO₂.HCl
Synonym	Fingolimod, Gilenya
For Use With (Application)	Sphingosine-1-phosphate Receptor Agonists

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Tocris Bioscience™ FTY 720

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