missing translation for 'onlineSavingsMsg'
Learn More

Tocris Bioscience™ FTY 720

Potent S1P receptor agonist; also immunosuppressant

147.00 € - 544.00 €

Specifications

Product Type Agonist
Target Proteins Sphingosine-1-phosphate Receptor
CAS 162359-56-0
Molecular Formula C19H33NO2.HCl
Formula Weight 343.93g/mol
View More Specs

Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
18792168
View Documents
Tocris Bioscience™
6176/10
10 mg
147.00 €
10mg
Please to purchase this item. Need a web account? Register with us today!
18761508
View Documents
Tocris Bioscience™
6176/50
50 mg
544.00 €
50mg
Please to purchase this item. Need a web account? Register with us today!
Description

Description

S1P receptor agonist; undergoes phosphorylation by sphingosine kinase 2, which then binds S1P1,3,4 and 5 receptors (EC50 values are 0.3 - 0.6 nM for S1P1, 4 and 5 and ∽3 nM for S1P3). Immunosuppresant; sequesters lymphocytes in lymph nodes, reducing autoimmune response. Suppresses the development of EAE (an in vivo model of MS). Orally bioavailable and blood-brain barrier permeable.
Specifications

Specifications

Agonist
162359-56-0
343.93g/mol
Store at -20°C
Sphingosine-1-phosphate Receptor
C19H33NO2.HCl
Fingolimod, Gilenya
Sphingosine-1-phosphate Receptor Agonists
Videos
SDS
Documents

Documents

Product Certifications

For Research Use Only

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.