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Tocris Bioscience™ FTY 720
Potent S1P receptor agonist; also immunosuppressant
147.00 € - 544.00 €
Specifications
| Product Type | Agonist |
|---|---|
| Target Proteins | Sphingosine-1-phosphate Receptor |
| CAS | 162359-56-0 |
| Molecular Formula | C19H33NO2.HCl |
| Formula Weight | 343.93g/mol |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18792168
|
Tocris Bioscience™
6176/10 |
10 mg |
147.00 €
10mg |
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|
18761508
|
Tocris Bioscience™
6176/50 |
50 mg |
544.00 €
50mg |
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Description
S1P receptor agonist; undergoes phosphorylation by sphingosine kinase 2, which then binds S1P1,3,4 and 5 receptors (EC50 values are 0.3 - 0.6 nM for S1P1, 4 and 5 and ∽3 nM for S1P3). Immunosuppresant; sequesters lymphocytes in lymph nodes, reducing autoimmune response. Suppresses the development of EAE (an in vivo model of MS). Orally bioavailable and blood-brain barrier permeable.Specifications
| Agonist | |
| 162359-56-0 | |
| 343.93g/mol | |
| Store at -20°C |
| Sphingosine-1-phosphate Receptor | |
| C19H33NO2.HCl | |
| Fingolimod, Gilenya | |
| Sphingosine-1-phosphate Receptor Agonists |
For Research Use Only