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KN-62, MedChemExpress
MedChemExpress KN-62 is a selective and reversible inhibitor of calmodulin-dependent protein kinase II (CaMK-II) with a Ki of 0.9 μM for rat brain CaMK-II. KN-62 directly binds to the calmodulin binding site of CaMK-II. KN-62 displays noncompetitive antagonism at P2X7 receptors in HEK293 cells, with an IC50 value of approximately 15 nM.
Brand: Medchem Express HY-13290
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Description
KN-62 is a selective and reversible inhibitor of calmodulin-dependent protein kinase II (CaMK-II) with a Ki of 0.9 μM for rat brain CaMK-II. KN-62 directly binds to the calmodulin binding site of CaMK-II. KN-62 displays noncompetitive antagonism at P2X7 receptors in HEK293 cells, with an IC50 value of approximately 15 nM.Specifications
| KN-62 | |
| Yellow | |
| C38H35N5O6S2 | |
| DMSO : ≥ 100 mg/mL (138.53 mM) | |
| 721.84 | |
| 98.27% | |
| Powder |
| 127191-97-3 | |
| Research | |
| 5 mg | |
| O=C(N1CCN(C2=CC=CC=C2)CC1)[C@H](CC3=CC=C(C=C3)OS(=O)(C4=CC=CC5=C4C=CN=C5)=O)N(C)S(=O)(C6=CC=CC7=C6C=CN=C7)=O | |
| 721.84 | |
| Research | |
| Cancer-Kinase/protease |
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Product Title
KN-62, MedChemExpress
Research purposes only
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