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Thermo Scientific™ T-REx™ Tango™ GHSR-bla U2OS Cells

The T-REx™ Tango™ GHSR-bla U2OS cells contain the human Growth Hormone Secretagogue Receptor (GHSR) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.

Brand:  Thermo Scientific™ K1819

Product Code. 10595664

  • 11960.00 € / Each
Estimated Shipment: 16-01-2025
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For Research Use Only. All usage must comply with product instructions.

This item is not returnable. View return policy

Description

Description

The T-REx™ Tango™ GHSR-bla U2OS cells contain the human Growth Hormone Secretagogue Receptor (GHSR) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.

The T-REx™ Tango™ GHSR-bla U2OS cells are functionally validated for Z' and EC50 concentrations of Ghrelin. In addition, T-REx™ Tango™ GHSR-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary.

For Academic pricing please login or contact us at discoverysciences@invitrogen.com.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

NM_198407
Dividing Cells
Tail from AVPR2 GPCR
Fluorescence
GHSR
T-REx™ Tango™ GHSR-bla U2OS cells (LiveBLAzer™-FRET B/G loading kit, solution D and other materials are required separately; please refer to the protocol). Includes: T-REx™ Tango™ GHSR-bla U2OS cells, T-REx™ Tango™ GHSR-bla U2OS assay protocol, certificate of analysis
GeneBLAzer™, Tango™
End Point
GHSR
U2OS
GPCR
Cell-based beta-arrestin recruitment
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.

Includes:
• T-REx™ Tango™ GHSR-bla U2OS cells
• T-REx™ Tango™ GHSR-bla U2OS Assay Protocol
• Certificate of Analysis

The T-REx™ Tango™ GHSR-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
T-REx™ Tango™ GHSR-bla U2OS Cells, 8 x 106 Cells, U2OS Cell Line, Fluorescent Detection Method, GPCRs Druggable Target, BLA (Beta-Lactamase) Reporter, Liquid Nitrogen Storage
FRET
G-Protein Coupled Receptor (GPCR)
Single Cell Clone Origin
8 x 106 Cells
U2OS
U2OS Cell
Tango™
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For Research Use Only. Not for use in diagnostic procedures.