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Thermo Scientific™ Tango™ ADORA1-bla U2OS Cells

The Tango™ ADORA1-bla U2OS cells contain the human Adenosine A1 receptor (ADORA1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.

Brand:  Thermo Scientific™ K1445

Product Code. 10467118

  • 12500.00 € / Each
Estimated Shipment: 16-01-2025
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For Research Use Only. All usage must comply with product instructions.

This item is not returnable. View return policy

Description

Description

The Tango™ ADORA1-bla U2OS cells contain the human Adenosine A1 receptor (ADORA1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line. This parental cell line stably expresses a beta-arrestin/TEV protease fusion protein and the beta-lactamase (bla) reporter gene under the control of a UAS response element.

The Tango™ ADORA1-bla U2OS cells have been functionally validated for Z' factor and EC50 concentrations of NECA. In addition, Tango™ ADORA1-bla U2OS cells have been tested for assay performance under variable conditions. These data are found in the Validation & Assay Performance Summary in the Manuals and Brochures section.

TRUSTED_SUSTAINABILITY
Specifications

Specifications

NM_000674.1
Dividing Cells
Tail from AVPR2 GPCR
GPCRs
ADORA1-bla U2OS cells, ADORA1-bla U2OS Assay Protocol, Certificate of Analysis
Tango™
BLA (Beta-Lactamase)
Dividing Cells
Tango™
Cell-based beta-arrestin recruitment
LiveBLAzer™-FRET B/G Loading Kit, Solution D and other materials are required separately; please refer to the protocol.

Includes:
• Tango™ ADORA1-bla U2OS cells
• Tango™ ADORA1-bla U2OS Assay Protocol
• Certificate of Analysis

The Tango™ ADORA1-bla U2OS cells are shipped on dry ice and should be stored in liquid nitrogen immediately upon receipt.
Fluorescence
ADORA1A
Pool of Stable Cells
2 x 106 Cells
ADORA1
U2OS
GPCR
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For Research Use Only. Not for use in diagnostic procedures.