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Tocris Bioscience™ uPSEM 817 tartrate
Highly potent and selective PSAM4-GlyR and PSAM4-5-HT3 chimeric ion channel agonist; brain-penetrant
Brand: Tocris Bioscience™ 6866/5
217.79 EUR valid until 2024-12-16
Use promo code "21630" to get your promotional price.
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Description
uPSEM 817 tartrate is a selective ultrapotent PSEM (uPSEM) agonist for α7L131G,Q139L,Y217F-GlyR (PSAM4-GlyR) and PSAM4-5-HT3 chimeric ion channels (EC50 values are 0.3 and 0.5 nM, respectively). Suppresses firing of layer 2/3 cortical neurons expressing PSAM4-GlyR in brain slices. Increases contralateral rotation in mice expressing PSAM4-GlyR unilaterally in the substantia nigra reticulata (LED 0.1 mg/kg).Specifications
2-Propoxy-7,8,9,10-tetrahydro-6 H-6,10-methanoazepino[4,5-g]quinoxaline L-tartrate | |
5 mg | |
C16H19N3O.C4H6O6 | |
98% |
2341833-14-3 | |
Pharmacologically Selective Effector Molecules/PSEM | |
419.43 |