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Tocris Bioscience™ uPSEM 817 tartrate

Highly potent and selective PSAM4-GlyR and PSAM4-5-HT3 chimeric ion channel agonist; brain-penetrant

278.00 € - 1070.00 €

Specifications

Chemical Name or Material 2-Propoxy-7,8,9,10-tetrahydro-6 H-6,10-methanoazepino[4,5-g]quinoxaline L-tartrate
CAS 2341833-14-3
Target Pharmacologically Selective Effector Molecules/PSEM
Molecular Formula C16H19N3O.C4H6O6
Formula Weight 419.43
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
18759836
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Tocris Bioscience™
6866/25
25 mg
1070.00 €
25mg
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18005742
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Tocris Bioscience™
6866/5
5 mg
278.00 €
5mg
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Description

Description

Selective ultrapotent PSEM (uPSEM) agonist for α7L131G,Q139L,Y217F-GlyR (PSAM4-GlyR) and PSAM4-5-HT3 chimeric ion channels (EC50 values are 0.3 and 0.5 nM, respectively). Suppresses firing of layer 2/3 cortical neurons expressing PSAM4-GlyR in brain slices. Increases contralateral rotation in mice expressing PSAM4-GlyR unilaterally in the substantia nigra reticulata (LED 0.1 mg/kg).
Specifications

Specifications

2-Propoxy-7,8,9,10-tetrahydro-6 H-6,10-methanoazepino[4,5-g]quinoxaline L-tartrate
Pharmacologically Selective Effector Molecules/PSEM
419.43
2341833-14-3
C16H19N3O.C4H6O6
98%
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Safety and Handling

Recommended Storage : Store at -20°C

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