Test
In the LanthaScreen™ Eu Kinase Binding Assay, binding of an Alexa Fluor™ conjugate or tracer such as Kinase Tracer 236 to a kinase is detected by addition of a Eu-labeled anti-tag antibody.
The CRE-bla Jurkat cell line contains a beta-lactamase reporter gene under control of a cAMP response element (CRE) stably integrated into Jurkat cells.
LanthaScreen™ GFP Cellular Assays allow for the analysis of post-translational modifications for a number of target proteins in an live-cell context.
Neurotrophins (NGF, BDNF, NT-3, and NT-4) and their transmembrane receptors (TrkA, TrkB, TrkC, and P75NTR) play important roles in the regulation of neuronal and non-neuronal cell proliferation, differentiation, survival, and death.
GeneBLAzer™ GIPR-CRE-bla HEK 293T Cells contain the human Gastric Inhibitory Peptide Receptor (GIPR).
GeneBLAzer™ GPR24-Gqi5-NFAT-bla CHO-K1 cells contain the human Melanin-concetrating hormone receptor (GPR24) stably integrated into the GeneBLAzer™ Gqi5-NFAT-bla CHO-K1 cell line.
The Tango™ SSTR1-bla U2OS cells contain the human Somatostatin Receptor 1 (SSTR1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
GeneBLAzer™ MC5R-CRE-bla CHO-K1 cells contain the human Melanocortin Receptor 5 (MC5R) stably integrated into the CellSensor™ CRE-bla CHO-K1 cell line.
The Tango™ GALR2-bla U2OS cells contain the human Galanin Receptor 2 (GALR2) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
The Tango™ CXCR1-bla U2OS cells contain the human Chemokine (C-X-C motif) receptor 1 (CXCR1) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
T-REx™ Tango™ P2RY14-bla U2OS cells contain the human purinergic receptor P2Y14 (P2RY14) under doxycycline inducible control linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
Tango™ EDG3-bla U2OS cells contain the human Endothelial Differentiation Gene 3 (EDG3) linked to a TEV protease site and a Gal4-VP16 transcription factor stably integrated into the Tango™ GPCR-bla U2OS parental cell line.
The CellSensor™ NFκB-bla ME-180 cell line contains a beta-lactamase reporter gene under control of the Nuclear Factor Kappa B (NFκB) response element stably integrated into ME-180 cells.
GeneBLAzer™ VDR DA (Division Arrested) cells and VDR-UAS-bla HEK 293T cells contain the ligand-binding domain (LBD) of the human Vitamin D receptor (VDR) fused to the DNAbinding domain of GAL4 stably integrated in the GeneBLAzer™UAS-bla HEK 293T cell line.
GeneBLAzer™ EDNRB-NFAT-bla HEK293T cells contain the human Endothelin Type B Recpetor (EDNRB) stably integrated into the CellSensor™ NFAT-bla HEK293T cell line.